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Novel nanomedicine inhibits progression of pancreatic cancer in mice

Anne Li 1/5/18 A new Tel Aviv University study pinpoints the inverse correlation between a known oncogene — a gene that promotes the development of cancer — and the expression of an oncosuppressor microRNA as the reason…...

Immune cells play key role in early breast cancer metastasis even before a tumor develops

Anne Li 1/5/18 Mount Sinai researchers have discovered that normal immune cells called macrophages, which reside in healthy breast tissue surrounding milk ducts, play a major role in helping early breast cancer cells leave the breast for…...

New guidelines on clinical trial design for patients with brain metastases

Anne LI 1/5/18 Clinical trials of new anti-cancer therapies have often excluded patients whose disease has spread to the brain or central nervous system (CNS) or, if such patients were allowed on trial, trials…...

Berry gives boost to cervical cancer therapy

Anne LI 1/5/18 According to the Centers for Disease Control and Prevention, approximately 12,000 women in the United States are diagnosed with cervical cancer each year. One of the most common treatments for cervical cancer is radiation. While…...

Gene therapy using CAR T-cells could provide long-term protection against HIV

Anne Li 1/5/18 Through gene therapy, researchers engineered blood-forming stem cells (hematopoietic stem/progenitor cells, or HSPCs) to carry chimeric antigen receptor (CAR) genes to make cells that can detect and destroy HIV-infected cells. These engineered cells not only destroyed the…...

Radiation therapy algorithm could reduce side effects, maintain effect against tumors

Anne Li 1/5/18 Researchers at North Carolina State University have developed a mathematical model for computing radiation therapy treatments that could substantially reduce patient side effects while delivering the same results as conventional radiation therapy. Cancer…...

Landmark genetic study better predicts stomach cancer

Anne LI 1/5/18 Although stomach cancer is treatable if detected early, diagnosis often occurs at an advanced stage, resulting in high mortality. A new study has identified genetic patterns in intestinal metaplasia (a precondition for stomach cancer) which help predict the…...

New cancer model shows genomic link between early-stage and invasive breast cancer types

Anne LI 1/5/18 A new genetic-based model may explain how a common form of early-stage breast cancer known as ductal carcinoma in situ (DCIS) progresses to a more invasive form of cancer, say researchers…...

Dirt-dwelling microbe produces potential anti-melanoma weapon

Anne LI 1/5/18 A type of soil-dwelling bacterium produces molecules that induce death in melanoma cells, research at Oregon State University shows. The molecule is a secondary metabolite, also known as a natural product, of…...

Viruses may boost immunotherapy in brain and breast cancer

Anne Li 1/5/18 Infecting tumours with viruses may boost the success of immunotherapy for brain and breast cancers, according to two new studies. Immunotherapy treatments can trigger impressive responses in patients with a handful of advanced cancers. But success…...

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